Should I be worried? Zoloft, Fluconazole, trouble sleeping, and anxiety.?

I have been taking Zoloft for almost three years now and take it to ease my anxiety disorder. I take the lowest possible dose. Recently I have been having a lot of trouble sleeping and have been hyperventilating much like I did prior to taking the medicine. When I get nervous, I focus on my breathing too much and I get worried about whether or not I'm getting enough air. It really takes a tole on my everyday life and makes me feel awful. I am currently on Thanksgiving vacation and have not been taking it at the time I generally do (in the morning with breakfast). Instead I have been taking it at around one in the afternoon or later, along with my other medications. I am on Ocella and Methylin as well. I was given a dose of Fluconazole two days ago, which is also when I started feeling anxious and having trouble breathing. I'm beginning to worry that there is a connection between the Fluconazole dose and my anxiety? Or is it simply because I am taking my medicine too late in the day. My mom suggested that I take another dose of Zoloft, but I'm worried that would make things worse. Would taking more be a bad idea? I'm freaking out and could really use some advice...